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KMID : 0354719960200030264
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Journal of Korean Diabetes Association
1996 Volume.20 No. 3 p.264 ~ p.272
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Incidence of Diabetes Mellitus in Yonchon County, Korea
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신찬수
김현규/김원배/박경수/김성연/조보연/이홍규/고창순/김용익
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Abstract
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Background :
@HN In recent decades, non-insulin dependent diabetes mellitus(NIDDM) became a major public health problem in Korea due to rapid economic growth. This study was performed to determined the incidence of NIDDM in Yonchon Count of Korea.
@HS Method :
@HN This study was performed as a prospective cohort study. We determined the 2-year incidence of NIDDM in 1193 Korean subjects who were found to be non-diabetic during the population-based diabetes prevalence study in 1993 and also participated
in
the
follow-up survey in 1995.
@HS Results :
@HN In two years, 67 subjects out of 1193 non-diabetic cohort developed diabetes, resulting in an annual rate of 2.8% as defined by World Health Orgaization criteria. After adjustment to the Korean standard population as of 1990, the incidence
rate
became 2.5% per annum. The age-adjusted incidence was significantly higher in men than in women(6.4% vs. 3.0%, x2trend=15.3, p<0.01). Subjects who converted to diabetes were older, more likely to be male, and had higher baseline fasting' and 2
hour
post-load glucose and triglyceride levels. Multiple logistic regression analysis revealed that age, male sex and baseline post-load plasma glucose concentrations are significant risk factors for the development of NIDDM.
@HS Conclusions :
@HN The incidence of NIDDM is much higher than expected and insulin resistance may not play an important role in this population. The reason for the rapid increase in the incidence should be further investigated.
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KEYWORD
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